Rams' place kicker Greg Zuerlein continued his excellent season going a flawless 9-for-9 on kick attempts, including three field goals and six extra points. Gurley added 104 scrimmage yards and two touchdowns, giving him 10 on the year - tying the career high he set in a dynamic rookie season.
That was quickly followed by Watkins and Jared Goff connecting for a 67-yard touchdown.
The Rams entered Sunday as the No. 1 team on third down, converting 49.0 percent of attempts.
The Los Angeles Rams released its final official injury report for its Week 9 game against the New York Giants late Friday evening, and listed no injuries for any of its players. It gave them 229 points, five more than their NFL-low total from all of last season. But a NY missed field goal as time expired in the second quarter kept the Rams with a 27-10 lead at halftime.More news: George HW Bush Openly Criticizes Trump in New Book
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Gurley capped the third-quarter scoring with a four-yard touchdown run, after linebacker Cory Littleton blocked his second punt in three games to give L.A. the ball on the NY 18-yard line.
On the next drive, the Rams reached the Giants' red zone again but had to settle for a Greg Zuerlein 27-yard field goal and a 10-7 lead in the first minute of the second quarter.
Any fears that the bye week might have stunted their momentum subsided early, as the Rams pummeled the New York Giants in every area of the game and recorded a 51-17 victory at MetLife Stadium. The Giants were still in the game, trailing 10-7, and had the Rams pinned back on a third-and-33 from their own 48.
After that, the Rams ran away with the game, completing big play after big play, starting with a 52-yard touchdown on a screen pass from Goff to Robert Woods that took place on a 3 and 33.
The 2016 Rams, through 16 games: 224 points. The Rams will be back at home at the Coliseum for the first time in over a month next week to play the Texans.